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How To Increase Platelets?*

July 31st, 2010

How To Increase Platelets? The most often asked question by any individual concerned with low platelets is, of course “how to increase platelets”?*

Increase Platelets.com is brought to you by Get Well Natural LLC as part of an internet sharing of health information. As the name implies there are Eastern Medicine dietary herbal practitioners who believe that the human body can increase platelets on its own with health support.*

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The importance of the blood platelet system in terms of keeping us with healthy blood platelet function cannot be overstated.  Blood platelets control bleeding among other functions according the the NIH and new research turns up new platelet functions, like platelet growth factors. In Eastern medicine, if the blood platelet function is supported, usually with dietary herbs and lifestyle adjustments, then the body can better support normal platelet function and levels.

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Aplastic Anemia

November 4th, 2013

What Is Aplastic Anemia?

Aplastic anemia (a-PLAS-tik uh-NEE-me-uh) is a blood disorder in which the body's bone marrow doesn't make enough new blood cells. Bone marrow is a sponge-like tissue inside the bones. It makes stem cells that develop into red blood cells, white blood cells, and platelets (PLATE-lets).

Red blood cells carry oxygen to all parts of your body. They also carry carbon dioxide (a waste product) to your lungs to be exhaled. White blood cells help your body fight infections. Platelets are blood cell fragments that stick together to seal small cuts or breaks on blood vessel walls and stop bleeding.

It's normal for blood cells to die. The lifespan of red blood cells is about 120 days. White blood cells live less than a day. Platelets live about 6 days. As a result, your bone marrow must constantly make new blood cells.

If your bone marrow can't make enough new blood cells, many health problems can occur. These problems include irregular heartbeats called arrhythmias (ah-RITH-me-ahs), an enlarged heart, heart failure, infections, and bleeding. Severe aplastic anemia can even cause death.

Overview

Aplastic anemia is a type of anemia. The term "anemia" usually refers to a condition in which your blood has a lower than normal number of red blood cells. Anemia also can occur if your red blood cells don't contain enough hemoglobin (HEE-muh-glow-bin). This iron-rich protein helps carry oxygen to your body.

In people who have aplastic anemia, the body doesn't make enough red blood cells, white blood cells, and platelets. This is because the bone marrow's stem cells are damaged. (Aplastic anemia also is called bone marrow failure.)

Many diseases, conditions, and factors can damage the stem cells. These conditions can be acquired or inherited. "Acquired" means you aren't born with the condition, but you develop it. "Inherited" means your parents passed the gene for the condition to you.

In many people who have aplastic anemia, the cause is unknown.

Outlook

Aplastic anemia is a rare but serious disorder. It can develop suddenly or slowly. The disorder tends to get worse over time, unless its cause is found and treated. Treatments for aplastic anemia include blood transfusions, blood and marrow stem cell transplants, and medicines.

With prompt and proper care, many people who have aplastic anemia can be successfully treated. Blood and marrow stem cell transplants may offer a cure for some people who have aplastic anemia.

What Causes Aplastic Anemia?

Damage to the bone marrow's stem cells causes aplastic anemia. When stem cells are damaged, they don't grow into healthy blood cells.

The cause of the damage can be acquired or inherited. "Acquired" means you aren't born with the condition, but you develop it. "Inherited" means your parents passed the gene for the condition to you.

Acquired aplastic anemia is more common, and sometimes it's only temporary. Inherited aplastic anemia is rare.

In many people who have aplastic anemia, the cause is unknown. Some research suggests that stem cell damage may occur because the body's immune system attacks its own cells by mistake.

Acquired Causes

Many diseases, conditions, and factors can cause aplastic anemia, including:

  • Toxins, such as pesticides, arsenic, and benzene.
  • Radiation and chemotherapy (treatments for cancer).
  • Medicines, such as chloramphenicol (an antibiotic rarely used in the United States).
  • Infectious diseases, such as hepatitis, Epstein-Barr virus, cytomegalovirus (si-to-MEG-ah-lo-VI-rus), parvovirus B19, and HIV.
  • Autoimmune disorders, such as lupus and rheumatoid arthritis.
  • Pregnancy. (Aplastic anemia that occurs during pregnancy often goes away after delivery.)

Sometimes, cancer from another part of the body can spread to the bone and cause aplastic anemia.

Inherited Causes

Certain inherited conditions can damage the stem cells and lead to aplastic anemia. Examples include Fanconi anemia, Shwachman-Diamond syndrome, dyskeratosis (DIS-ker-ah-TO-sis) congenita, and Diamond-Blackfan anemia.

Who Is at Risk for Aplastic Anemia?

Aplastic anemia is a rare but serious blood disorder. People of all ages can develop aplastic anemia. However, it's most common in adolescents, young adults, and the elderly. Men and women are equally likely to have aplastic anemia.

The disorder is two to three times more common in Asian countries.

Your risk of aplastic anemia is higher if you:

  • Have been exposed to toxins
  • Have taken certain medicines or had radiation or chemotherapy (treatments for cancer)
  • Have certain infectious diseases, autoimmune disorders, or inherited conditions

For more information, go to "What Causes Aplastic Anemia?"

What Are the Signs and Symptoms of Aplastic Anemia?

Lower than normal numbers of red blood cells, white blood cells, and platelets cause most of the signs and symptoms of aplastic anemia.

Signs and Symptoms of Low Blood Cell Counts

Red Blood Cells

The most common symptom of a low red blood cell count is fatigue (tiredness). A lack of hemoglobin in the blood causes fatigue. Hemoglobin is an iron-rich protein in red blood cells. It helps carry oxygen to the body.

A low red blood cell count also can cause shortness of breath; dizziness, especially when standing up; headaches; coldness in your hands or feet; pale skin; and chest pain.

If you don't have enough hemoglobin-carrying red blood cells, your heart has to work harder to move the reduced amount of oxygen in your blood. This can lead to arrhythmias (irregular heartbeats), a heart murmur, an enlarged heart, or even heart failure.

White Blood Cells

White blood cells help fight infections. Signs and symptoms of a low white blood cell count include fevers, frequent infections that can be severe, and flu-like illnesses that linger.

Platelets

Platelets stick together to seal small cuts or breaks on blood vessel walls and stop bleeding. People who have low platelet counts tend to bruise and bleed easily, and the bleeding may be hard to stop.

Common types of bleeding associated with a low platelet count include nosebleeds, bleeding gums, pinpoint red spots on the skin, and blood in the stool. Women also may have heavy menstrual bleeding.

Other Signs and Symptoms

Aplastic anemia can cause signs and symptoms that aren't directly related to low blood cell counts. Examples include nausea (feeling sick to your stomach) and skin rashes.

Paroxysmal Nocturnal Hemoglobinuria

Some people who have aplastic anemia have a red blood cell disorder called paroxysmal (par-ok-SIZ-mal) nocturnal hemoglobinuria (HE-mo-glo-bi-NOO-re-ah), or PNH. Most people who have PNH don't have any signs or symptoms.

If symptoms do occur, they may include:

  • Shortness of breath
  • Swelling or pain in the abdomen or swelling in the legs caused by blood clots
  • Blood in the urine
  • Headaches
  • Jaundice (a yellowish color of the skin or whites of the eyes)

In people who have aplastic anemia and PNH, either condition can develop first.

How Is Aplastic Anemia Diagnosed?

Your doctor will diagnose aplastic anemia based on your medical and family histories, a physical exam, and test results.

Once your doctor knows the cause and severity of the condition, he or she can create a treatment plan for you.

Specialists Involved

If your primary care doctor thinks you have aplastic anemia, he or she may refer you to a hematologist. A hematologist is a doctor who specializes in treating blood diseases and disorders.

Medical and Family Histories

Your doctor may ask questions about your medical history, such as whether:

  • You've had anemia or a condition that can cause anemia
  • You have shortness of breath, dizziness, headaches, or other signs and symptoms of anemia
  • You've been exposed to certain toxins or medicines
  • You've had radiation or chemotherapy (treatments for cancer)
  • You've had infections or signs of infections, such as fever
  • You bruise or bleed easily

Your doctor also may ask whether any of your family members have had anemia or other blood disorders.

Physical Exam

Your doctor will do a physical exam to check for signs of aplastic anemia. He or she will try to find out how severe the disorder is and what's causing it.

The exam may include checking for pale or yellowish skin and signs of bleeding or infection. Your doctor may listen to your heart and lungs for abnormal heartbeats and breathing sounds. He or she also may feel your abdomen to check the size of your liver and feel your legs for swelling.

Diagnostic Tests

Many tests are used to diagnose aplastic anemia. These tests help:

  • Confirm a diagnosis of aplastic anemia, look for its cause, and find out how severe it is
  • Rule out other conditions that may cause similar symptoms
  • Check for paroxysmal nocturnal hemoglobinuria (PNH)

Complete Blood Count

Often, the first test used to diagnose aplastic anemia is a complete blood count(CBC). The CBC measures many parts of your blood.

This test checks your hemoglobin and hematocrit (hee-MAT-oh-crit) levels. Hemoglobin is an iron-rich protein in red blood cells. It carries oxygen to the body. Hematocrit is a measure of how much space red blood cells take up in your blood. A low level of hemoglobin or hematocrit is a sign of anemia.

The normal range of these levels varies in certain racial and ethnic populations. Your doctor can explain your test results to you.

The CBC also checks the number of red blood cells, white blood cells, and platelets in your blood. Abnormal results may be a sign of aplastic anemia, an infection, or another condition.

Finally, the CBC looks at mean corpuscular (kor-PUS-kyu-lar) volume (MCV). MCV is a measure of the average size of your red blood cells. The results may be a clue as to the cause of your anemia.

Reticulocyte Count

A reticulocyte (re-TIK-u-lo-site) count measures the number of young red blood cells in your blood. The test shows whether your bone marrow is making red blood cells at the correct rate. People who have aplastic anemia have low reticulocyte levels.

Bone Marrow Tests

Bone marrow tests show whether your bone marrow is healthy and making enough blood cells. The two bone marrow tests are aspiration (as-pih-RA-shun) and biopsy.

Bone marrow aspiration might be done to find out if and why your bone marrow isn't making enough blood cells. For this test, your doctor removes a small amount of bone marrow fluid through a needle. The sample is looked at under a microscope to check for faulty cells.

A bone marrow biopsy might be done at the same time as an aspiration or afterward. For this test, your doctor removes a small amount of bone marrow tissue through a needle.

The tissue is checked for the number and types of cells in the bone marrow. In aplastic anemia, the bone marrow has a lower than normal number of all three types of blood cells.

Other Tests

Other conditions can cause symptoms similar to those of aplastic anemia. Thus, other tests might be needed to rule out those conditions. These tests may include:

  • X ray, computed tomography (CT) scan, or an ultrasound imaging test. These tests can show enlarged lymph nodes in your abdomen. Enlarged lymph nodes may be a sign of blood cancer. Doctors also may use these tests to look at the kidneys and the bones in the arms and hands, which are sometimes abnormal in young people who have Fanconi anemia. This type of anemia can lead to aplastic anemia.
  • Chest x ray. This test creates pictures of the structures inside your chest, such as your heart, lungs, and blood vessels. A chest x ray may be used to rule out infections.
  • Liver tests and viral studies. These tests are used to check for liver diseases and viruses.
  • Tests that check vitamin B12 and folate levels in the blood. These tests can help rule out anemia caused by vitamin deficiency.

Your doctor also may recommend blood tests for PNH and to check your immune system for proteins called antibodies. (Antibodies in the immune system that attack your bone marrow cells may cause aplastic anemia.)

How Is Aplastic Anemia Treated?

Treatments for aplastic anemia include blood transfusions, blood and marrow stem cell transplants, and medicines. These treatments can prevent or limit complications, relieve symptoms, and improve quality of life.

Blood and marrow stem cell transplants may cure the disorder in some people who are eligible for a transplant. Removing a known cause of aplastic anemia, such as exposure to a toxin, also may cure the condition.

Who Needs Treatment

People who have mild or moderate aplastic anemia may not need treatment as long as the condition doesn't get worse. People who have severe aplastic anemia need medical treatment right away to prevent complications.

People who have very severe aplastic anemia need emergency medical care in a hospital. Very severe aplastic anemia can be fatal if it's not treated right away.

Blood Transfusions

Blood transfusions can help keep blood cell counts at acceptable levels. A blood transfusion is a common procedure in which blood is given to you through an intravenous (IV) line in one of your blood vessels.

Transfusions require careful matching of donated blood with the recipient's blood.

Blood transfusions help relieve the symptoms of aplastic anemia, but they're not a permanent treatment.

Blood and Marrow Stem Cell Transplants

A blood and marrow stem cell transplant replaces damaged stem cells with healthy ones from another person (a donor).

During the transplant, which is like a blood transfusion, you get donated stem cells through a tube placed in a vein in your chest. Once the stem cells are in your body, they travel to your bone marrow and begin making new blood cells.

Blood and marrow stem cell transplants may cure aplastic anemia in people who can have this type of treatment. The transplant works best in children and young adults with severe aplastic anemia who are in good health and who have matched donors.

Older people may be less able to handle the treatments needed to prepare the body for the transplant. They're also more likely to have complications after the transplant.

If you have aplastic anemia, talk with your doctor about whether a blood and marrow stem cell transplant is an option for you.

Medicines

If you have aplastic anemia, your doctor may prescribe medicines to:

  • Stimulate your bone marrow
  • Suppress your immune system
  • Prevent and treat infections

Medicines To Stimulate Bone Marrow

Man-made versions of substances that occur naturally in the body can stimulate the bone marrow to make more blood cells. Examples of these types of medicines include erythropoietin and colony-stimulating factors.

These medicines have some risks. You and your doctor will work together to decide whether the benefits of these medicines outweigh the risks. If this treatment works well, it can help you avoid the need for blood transfusions.

Medicines To Suppress the Immune System

Research suggests that aplastic anemia may sometimes occur because the body's immune system attacks its own cells by mistake. For this reason, your doctor may prescribe medicines to suppress your immune system.

These medicines allow your bone marrow to start making blood cells again. They also may help you avoid the need for blood transfusions.

Medicines that suppress the immune system don't cure aplastic anemia. However, they can relieve its symptoms and reduce complications. These medicines often are used for people who can't have blood and marrow stem cell transplants or who are waiting for transplants.

Three medicines - often given together - can suppress the body's immune system. They are antithymocyte globulin (ATG), cyclosporine, and methylprednisolone.

It may take a few months to notice the effects of these medicines. Most often, as blood cell counts rise, symptoms lessen. Blood cell counts in people who respond well to these medicines usually don't reach normal levels. However, the blood cell counts often are high enough to allow people to do their normal activities.

People who have aplastic anemia may need long-term treatment with these medicines.

Medicines that suppress the immune system can have side effects. They also may increase the risk of developing leukemia (lu-KE-me-ah) or myelodysplasia (MI-e-lo-dis-PLA-ze-ah; MDS). Leukemia is a cancer of the blood cells. MDS is a condition in which the bone marrow makes too many faulty blood cells.

Medicines To Prevent and Treat Infections

If you have aplastic anemia, you might be at risk for infections due to low white blood cell counts. Your doctor may prescribe antibiotic and antiviral medicines to prevent and treat infections.

Living With Aplastic Anemia

With prompt and proper care, most people who have aplastic anemia can be successfully treated, and some may be cured.

Most people who have the disorder are able to go back to their normal routines after treatment. However, it may take some time to get good results from treatment. You may need repeated treatments, or you may need to try several treatments to find one that works.

Get ongoing medical care to make sure the disorder doesn't worsen and to check for possible complications.

Ongoing Care

Treatment for aplastic anemia may cause side effects or complications. Talk with your doctor about how to cope with these issues.

People who have aplastic anemia might be at higher risk for infections due to low white blood cell counts. Ask your doctor about ways to lower your risk for infection. For example, you may want to:

  • Stay away from people who are sick and avoid large crowds of people.
  • Avoid certain foods that can expose you to bacteria, such as uncooked foods.
  • Wash your hands often.
  • Brush and floss your teeth and get regular dental care to reduce the risk of infections in your mouth and throat.
  • Get a yearly flu shot and pneumonia vaccine. Ask your doctor whether these shots will benefit you.

Know the signs of infection, such as fever. Call your doctor right away if you think you have an infection.

Physical Activity

Talk with your doctor about what types and amounts of physical activity are safe for you. You may want to avoid activities that cause chest pain or shortness of breath. You also may want to stay away from activities that could result in injuries and bleeding, such as contact sports.

Support Groups

You or your family members may find it helpful to know about resources that can give you emotional support and information about aplastic anemia.

Your doctor or hospital social worker may have information about counseling and support services. They also may be able to refer you to support groups that offer help with financial planning, because treatment for aplastic anemia can be costly.

Clinical Trials

The National Heart, Lung, and Blood Institute (NHLBI) is strongly committed to supporting research aimed at preventing and treating heart, lung, and blood diseases and conditions and sleep disorders.

Researchers have learned a lot about anemia and other blood diseases and conditions over the years. That knowledge has led to advances in medical knowledge and care.

Many questions remain about blood diseases and conditions, including aplastic anemia. The NHLBI continues to support research aimed at learning more about these illnesses.

For example, NHLBI-supported research on aplastic anemia includes studies that explore:

  • How certain medicines and therapies can help treat aplastic anemia and improve quality of life for people who have the disorder
  • The safety and effectiveness of different methods of blood and marrow stem cell transplant for treating aplastic anemia
  • How to improve existing treatments for aplastic anemia

Much of this research depends on the willingness of volunteers to take part in clinical trials. Clinical trials test new ways to prevent, diagnose, or treat various diseases and conditions.

For example, new treatments for a disease or condition (such as medicines, medical devices, surgeries, or procedures) are tested in volunteers who have the illness. Testing shows whether a treatment is safe and effective in humans before it is made available for widespread use.

By taking part in a clinical trial, you can gain access to new treatments before they're widely available. You also will have the support of a team of health care providers, who will likely monitor your health closely. Even if you don't directly benefit from the results of a clinical trial, the information gathered can help others and add to scientific knowledge.

If you volunteer for a clinical trial, the research will be explained to you in detail. You'll learn about treatments and tests you may receive, and the benefits and risks they may pose. You'll also be given a chance to ask questions about the research. This process is called informed consent.

If you agree to take part in the trial, you'll be asked to sign an informed consent form. This form is not a contract. You have the right to withdraw from a study at any time, for any reason. Also, you have the right to learn about new risks or findings that emerge during the trial.

For more information about clinical trials related to aplastic anemia, talk with your doctor. You also can visit the following Web sites to learn more about clinical research and to search for clinical trials:

For more information about clinical trials for children, visit the NHLBI's Children and Clinical Studies Web page.

Links to Other Information About Aplastic Anemia

NHLBI Resources

Non-NHLBI Resources

Clinical Trials

Source: http://www.nhlbi.nih.gov/health/health-topics/topics/aplastic/

Myelodysplastic Syndromes (MDS)

July 30th, 2013
Myelodysplastic Syndromes Isolated Del

Myelodysplastic syndrome with isolated del (5q).

Myelodysplastic Syndromes MDS – Your bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. It contains immature cells, called stem cells. The stem cells can develop into the red blood cells that carry oxygen through your body, the white blood cells that fight infections, and the platelets that help with blood clotting. If you have a myelodysplastic syndrome, the stem cells do not mature into healthy blood cells. This leaves less room for healthy cells, which can lead to infection, anemia, or easy bleeding.

Symptoms of Myelodysplastic Syndromes MDS

Myelodysplastic syndromes often do not cause early symptoms and are sometimes found during a routine blood test. If you have symptoms, they may include

  • Shortness of breath
  • Weakness or feeling tired
  • Skin that is paler than usual
  • Easy bruising or bleeding
  • Pinpoint spots under the skin caused by bleeding
  • Fever or frequent infections

Myelodysplastic syndromes are rare. People at higher risk are over 60, have had chemotherapy or radiation therapy, or have been exposed to certain chemicals. Treatment options include transfusions, drug therapy, chemotherapy, and blood or bone marrow stem cell transplants.

NIH National Cancer Institute

Source: http://www.nlm.nih.gov/medlineplus/myelodysplasticsyndromes.html

Chronic Lymphocytic Leukemia (CLL)

July 5th, 2013
Chronic Lymphocytic Leukemia CLL Histiocytic Cells

Immunoglobulin-rich histiocytic cells (crystal storage histiocytosis) in a lymph node involved with SLL/CLL.

Chronic lymphocytic leukemia CLL is cancer of a type of white blood cells called lymphocytes.

See also:

Causes of Chronic Lymphocytic Leukemia CLL

Chronic lymphocytic leukemia (CLL) causes a slow increase in white blood cells called B lymphocytes, or B cells. Cancer cells spread through the blood and bone marrow, and can also affect the lymph nodes or other organs such as the liver and spleen. CLL eventually causes the bone marrow to fail.

IThe cause of CLL is unknown. There is no link to radiation, cancer-causing chemicals, or viruses.

This cancer mostly affects adults, around age 70. It is rarely seen under age 40. The disease is more common in Jewish people of Russian or East European descent.

Symptoms of Chronic Lymphocytic Leukemia CLL

Symptoms usually develop slowly over time. Many cases of CLL are detected by blood tests done in people for other reasons or who do not have any symptoms.

Symptoms that can occur include:

Exams and Tests for Chronic Lymphocytic Leukemia CLL

Patients with CLL usually have a higher-than-normal white blood cell count.

Tests to diagnose and assess CLL include:

  • Complete blood count (CBC) with white blood cell differential
  • Bone marrow biopsy
  • CT scan of the chest, abdomen, and pelvis
  • Immunoglobulin testing
  • Flow cytometry test of the white blood cells

If your doctor discovers you have CLL, tests will be done to see how much the cancer has spread. This is called staging.

There are two systems used to stage CLL:

  • The Rai system uses numbers 0 to IV to group CLL into low-, intermediate-, and high-risk categories. Generally, the higher the stage number, the more advanced the cancer.
  • The Binet system uses letters A-C to stage CLL according to how many lymph node groups are involved and whether you have a drop in the number of red blood cells or platelets.

Some newer tests look at the chromosomes inside the cancer cells. The results can help your doctor better determine your treatment.

Treatment of Chronic Lymphocytic Leukemia CLL

If you have early stage CLL, your doctor will closely monitor you. Usually, no medicines or other treatment is given for early-stage CLL, unless you have:

  • A high-risk type of CLL
  • Infections that keep coming back
  • Leukemia that is rapidly getting worse
  • Low blood and platelet counts
  • Fatigue, loss of appetite, weight loss, or night sweats
  • Painful swollen lymph nodes

Chemotherapy medicines are used to treat CLL. Common ones include:

  • Fludarabine, chlorambucil, cyclophosphamide (Cytoxan), and rituximab (Rituxan) used alone or together.
  • Alemtuzumab (Campath) for patients with CLL that did not get better with fludarabine.
  • Bendamustine for patients with CLL that has come back after initial treatment.

Rarely, radiation may be used for painfully enlarged lymph nodes. Blood transfusions or platelet transfusions may be required if blood counts are low.

Bone marrow or stem cell transplantation may be used in younger patients with advanced or high-risk CLL. A transplant is the only therapy that offers a potential cure for CLL.

Outlook (Prognosis) of Chronic Lymphocytic Leukemia CLL

How well a patient does depends on the stage of the cancer. About half of patients diagnosed in the early stages of the disease live more than 12 years.

Possible Complications of Chronic Lymphocytic Leukemia (CLL)

  • Autoimmune hemolytic anemia
  • Bleeding from low platelet count
  • Hypogammaglobulinemia, a condition in which you have lower levels of antibodies, which increases your risk of infection
  • Idiopathic thrombocytopenic purpura (ITP)
  • Infections that keep coming back (recur)
  • Overwhelming fatigue
  • Other cancers, including a much more aggressive lymphoma (Richter’s transformation)
  • Side effects of chemotherapy

When to Contact a Medical Professional

Call health care provider if you develop enlarged lymph nodes or unexplained fatigue, bruising, excessive sweating, or weight loss.

Alternative Names for Chronic Lymphocytic Leukemia (CLL)

CLL; Leukemia – chronic lymphocytic (CLL)

References

Kantarjian H, O’Brien S. The chronic leukemias. In: Goldman L, Ausiello D, eds. Cecil Textbook of Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011: chap 190.

National Comprehensive Cancer Network. National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology: Non-Hodgkin’s Lymphomas. 2012. Version 1.2012.

Update Date: 3/14/2012

Updated by: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M. Health Solutions, Ebix, Inc.

Browse the Encyclopedia

Source: http://www.nlm.nih.gov/medlineplus/ency/article/000532.htm

Normal Platelet Function

September 15th, 2012

Normal Platelet Function – This article is meant to provide you with an idea of what normal platelet function and normal platelet levels are, and the problems that can arise when your platelets are not functioning normally or are not within normal levels.

Blood Platelets

The Blood Platelets are the irregularly shaped things between the blood cells.

To learn more about blood platelets in general, you might first want to check out our useful overview of blood platelets. The dime version is that blood platelets are irregularly shaped, sticky blood cells. They are considered “cell fragments”, have no nucleus, and with the help of other minerals, vitamins and proteins, they bunch together to stop the bleeding when you sustain an injury or experience blood loss. Platelet function conditions to watch out for include a low platelet count, a high platelet count, and abnormal platelet function.*

What Is Normal Platelet Function?

According to the NIH, you should typically have 150,000 to 450,000 platelets per microliter (one millionth of a liter) of blood in your body. Watch out for:

  • Levels that are too much lower than that (especially below 50,000 platelets per microliter) mean you could have thrombocytopenia. This can mean there are not enough platelets to properly clot and staunch blood flow after an injury, leading to prolonged and excessive bleeding.
  • Levels that are too much higher than that (especially above 750,000 platelets per microliter) mean you could have thrombocytosis. This can cause unnecessary, dangerous blood clots that can travel to the brain and the heart.
  • Lastly, you want to make sure the platelets you do have are functioning properly, and clotting when needed.

In addition to clotting, properly functioning platelets modulate the inflammatory process, and slowly shrink clots at the site of an injury, as your body repairs the damage and the clot is no longer needed.

How Do You Maintain Normal Platelet Function?

Red and White Blood Cell with Platelet

Scanning microscope shot of a red blood cell left, platelet center, white blood cell right. From http://en.wikipedia.org/wiki/Platelet

The bad news is you can’t completely prevent a low blood platelet count (thrombocytopenia), a high blood platelet count (thrombocytosis) and abnormal platelet function, but what you can do is lower your levels of risk. High blood pressure, high blood cholesterol, diabetes and smoking all put you at much greater risk for blood clotting.

To reduce these risks, you can:

  • Eat a healthy diet
  • Exercise regularly
  • Quit smoking
  • Manage your blood sugar levels.
  • Find out if your age, race, gender, weight or family history put you at greater risk of developing these conditions
  • Regularly check in with your health care professional (including having your blood platelet levels checked)

If you are past prevention, and would like find out more about treatment for these conditions, please take a look at the individual articles for a more detailed list of treatments to explore for a low platelet count, a high platelet count, and abnormal platelet function.*

Normal Platelet Function Conclusion

Proper platelet function and levels are very important to overall health, though we still have a lot to learn about some of the causes irregular platelet levels and abnormal platelet function. Always educate yourself, and as we mentioned earlier, consult with your health care professional when dealing with these types of conditions. Healthy lifestyle and nutrition are vital to overall health according to the National Institutes of Health, conventional and traditional medicine, and good common sense.*

Thanks,

Get Well Natural LLC

Sources:

http://www.fi.edu/learn/heart/blood/platelet.html
http://en.wikipedia.org/wiki/Platelet
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475837
http://www.diabetes.org/diabetes-basics/prevention/checkup-america/

Abnormal Platelet Function

April 13th, 2013

Abnormal Platelet Function – This article is meant to provide you with an idea of what abnormal platelet levels are, and the problems they can cause. “Abnormal platelet function” means platelets that don’t function properly, as opposed to a low platelet count or high platelet count with otherwise normal platelet function.

Blood Platelets

The Blood Platelets are the irregularly shaped things between the blood cells. Platelets are a ‘cell fragment’ and have no nucleus.

For an overview of blood platelets in general, first check out our handy primer on blood platelets. In short, blood platelets are irregularly shaped, sticky blood cells. They are considered “cell fragments”, have no nucleus, and with the help of other minerals, vitamins and proteins, bunch together to stop the bleeding when you sustain an injury or are experiencing blood loss. Platelet function conditions to watch out for are a high blood platelet count, a low blood platelet count, and abnormal platelet function.*

What Is Abnormal Platelet Function?

Abnormal platelet function (also known as thrombasthenia or Glanzmann’s thrombasthenia) is a very rare bleeding disorder that results from a blood abnormality. Remember when we said that a few other substances, including protein help platelets form blood clots? Well according to the National Institute of Health, in thrombasthenia, your platelets are producing defective or low levels of the receptors for the protein fibrin, a key player in the blood clotting process. As a result, you bleed for longer than you would with normal functioning platelets. As Wikipedia says, some people with thrombasthenia only suffer mild bruising, while others can have serious, life-threatening hemorrhages.

What Causes Abnormal Platelet Function (thrombasthenia)?

Thrombasthenia can either be inherited at birth or developed as the result of an autoimmune disorder. Autoimmune disorders involve abnormal immune function, in this case an inappropriate and harmful response from the body’s immune system to substances normally found in the body.

How Can I Treat Abnormal Platelet Function?

Modern medicine still has a lot to learn about thrombasthenia. This includes whether or not, as of yet unidentified factors, play a big role in prolonged bleeding. Wikipedia lists the following possible treatments for abnormal platelet function:

Red and White Blood Cell with Platelet

Scanning microscope shot of a red blood cell left, platelet center, white blood cell right. From http://en.wikipedia.org/wiki/Platelet

  • Dental hygiene lessens gingival bleeding
  • Avoidance of antiplatelet agents such as aspirin and other anti-inflammatory drugs (NSAIDs) such as ibuprofen and naproxen, and anticoagulants
  • Iron or folate supplementation may be necessary if excessive or prolonged bleeding has caused anemia
  • Hepatitis B vaccine
  • Antifibrinolytic drugs such as tranexamic acid or ε-aminocaproic acid (Amicar)
  • Desmopressin (DDAVP) does not normalize the bleeding time in Glanzmann’s thrombasthenia but anecdotally improves hemostasis
  • Hormonal contraceptives to control excessive menstrual bleeding
  • Topical agents such as gelfoam, fibrin sealants, polyethylene glycol polymers, custom dental splints
  • Platelet transfusions (only if bleeding is severe; risk of platelet alloimmunization)
  • Recombinant factor VIIa
  • Hematopoietic stem cell transplantation (HSCT) for severe recurrent hemorrhages

Abnormal Platelet Function Conclusion

Clearly abnormal platelet function is not trivial and remains somewhat mysterious. Always educate yourself and consult with your health care professional when approaching these types of conditions. Healthy lifestyle and nutrition are vital to overall health according to the National Institutes of Health, conventional and traditional medicine, and good common sense.*

Thanks,

Get Well Natural LLC

Sources:
http://www.fi.edu/learn/heart/blood/platelet.html
http://en.wikipedia.org/wiki/Platelet
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475837
http://en.wikipedia.org/wiki/Fibrin

High Blood Platelets

August 21st, 2012

A healthy human has 150,000 to 450,000 platelets (thrombocytes) per microliter of blood in the body. If your body is producing more platelets than that, then you could have a high blood platelet count. If your high blood platelet count is due to a bone marrow disorder, or a cause unknown, it is referred to as thrombocythemia (also, primary or essential thrombocythemia). If your high blood platelet count is the result of another disease or condition, it is called secondary or reactive thrombocytosis. According to the NIH, thrombocythemia is less common, but potentially more dangerous, than secondary thrombocytosis.

What Are the Symptoms of High Blood Platelets?

Many people who have a high blood platelet count do not experience any symptoms at all. This is good, but you should still have the situation monitored by a physician and pay close attention to your health. If your bone marrow is producing more than 750,000 or 1 million platelets per microliter of blood, this should be serious cause for concern. The biggest complication you want to worry about from high blood platelets is blood clotting. Blood clots can occur anywhere in the body, but happen most often in the brain and the extremities.

Potential signs of blood clots in the body:

  • Dizziness
  • Seizures and stroke
  • Shortness of breath
  • Discomfort in the upper body
  • Numbness or tingling in the extremities

Should I Be Worried about High Blood Platelets?

As we said earlier, many people with a high blood platelet count experience no outward symptoms. But it is still something to monitor, because a very high blood platelet count can potentially lead to blood clotting and a serious stroke or seizure. And a blood platelet count of over 1 million can also occasionally cause excessive bleeding. If you are experiencing any symptoms you believe may be related to high blood platelets, you should consult a physician immediately.

What Causes High Blood Platelets?

According to the Mayo Clinic, in primary thrombocythemia, a high blood platelet count is caused by a bone marrow disorder where faulty cells in the bone marrow are producing too many platelets (and the platelets being produced are abnormal). In secondary thrombocytosis, however, the underlying condition is the cause of the high blood platelet count. Such conditions include cancer, anemia, tuberculosis and inflammatory bowel disease.

What Can I Do to Prevent and Treat High Blood Platelets?

Well, we’re glad you asked. You can’t actually prevent primary thrombocythemia. But if you have it, you can take steps to help prevent blood clots. High blood pressure, high cholesterol, obesity, diabetes and growing old all put you at greater risk for developing blood clots.
To mitigate these risks, the May Clinic recommends:

  • Eat healthily – Go heavy on the fruits and vegetables, but light on trans fats and saturated fats
  • Exercise often
  • Stop smoking!

If you do happen to develop blood clots, your doctor will prescribe medication. And forgive us for stating the obvious, but to deal with secondary thrombocytosis, you need to treat its underlying cause.
Article Sources:
http://www.nhlbi.nih.gov/health/health-topics/topics/thrm
http://www.mayoclinic.com/health/thrombocytosis/DS01088
http://en.wikipedia.org/wiki/Thrombocytosis

Low Blood Platelets

July 10th, 2012

Normally, you should have 150,000 to 450,000 platelets per microliter (one millionth of a liter) of blood in your body. If your blood platelet count falls below that, then you could have a low blood platelet count. The technical term for a problematic low platelet count (especially 50,000 platelets per microliter and lower) is thrombocytopenia.

What Are the Symptoms of Low Blood Platelets (Thrombocytopenia)?

Blood Platelets

The Blood Platelets are the irregularly shaped things between the blood cells.

The platelets in your blood are responsible for clotting to prevent excessive bleeding. If your blood platelet count is too low, mild to serious bleeding can occur.

Watch out for excessive bruising or external bleeding, such as:

  • Prolonged bleeding from wounds or cuts
  • Bleeding from brushing teeth (this can also happen if you don’t brush your teeth enough!)
  • Heavy menstrual flow in women
  • Excessive bleeding after surgery

In rare cases you can experience internal bleeding, a very serious problem that can lead to bleeding into vital organs or the brain, and can be fatal.

Should I Be Worried About Low Blood Platelets?

If you are experiencing any of the symptoms mentioned above (excessive external or internal bleeding), you should consult a physician.

If you are concerned that your platelet count may be low, but are not experiencing any symptoms, the answer is a little trickier. If you had your blood platelet count measured, here are some helpful benchmarks:

  • 150,000 – 450,000 platelets per microliter: Looking good!
  • 140,000 – 150,000 platelets per microliter: This is the low end of normal. You may want to have your blood platelet count measured again in a few weeks to see if it has increased at all.
  • Less than 50,000 platelets per microliter: This is generally what is defined as thrombocytopenia. Many people with thrombocytopenia experience mild bleeding or no symptoms at all, but it something to be concerned about.

What Causes Low Blood Platelets?

According to the National Heart Lung and Blood Institute, there are a number of causes for low blood platelets.

Red and White Blood Cell with Platelet

Scanning microscope shot of a red blood cell left, platelet center, white blood cell right. From http://en.wikipedia.org/wiki/Platelet

1) Your bone marrow isn’t creating enough platelets. This can be due to a number of reasons:

  • Cancer Leukemia and lymphoma can damage bone marrow and blood cells, as can popular treatments for these types of cancer, like radiation and chemotherapy.
  • Excessive Alcohol Consumption
  • Exposure to Toxic Chemicals
  • Vitamin B12 Deficiency
  • A host of viruses, from chickenpox to AIDS, can lower your blood platelets.
  • Genetic Factors
  • Some common medications can affect blood platelet counts, such as diuretics (popular blood pressure medication) and even aspirin and ibuprofen.

2) Your bone marrow is ok, but your body is destroying too many blood platelets. This can be caused by:

  • Autoimmune Diseases
  • Infection or Virus
  • Some antibiotics and seizure medications can cause low blood platelets. And the NIH also described a problem that can happen with the medication Heparin: “Heparin is a medicine commonly used to prevent blood clots. But an immune reaction may trigger the medicine to cause blood clots and thrombocytopenia. This condition is called heparin-induced thrombocytopenia (HIT). HIT rarely occurs outside of a hospital.”
  • Pregnancy

3) An enlarged spleen can also hold more platelets than it should, and prevent them from circulating to the rest of the body, or hamper proper bone marrow function. A healthy spleen holds 1/3 of all the blood platelets in your body.

How can I avoid low blood platelets and keep by blood platelet count at healthy levels?

The National Heart Lung and Blood Institute recommends the following suggestions for low blood platelet prevention:

  • Don’t drink in excess. Too much alcohol in the bloodstream slows down the process of creating blood platelets.
  • Avoid contact with toxic chemicals like pesticides and arsenic (probably a good idea anyway, for a host of health reasons).
  • Be careful of medicines known to cause low blood platelets, such as the aforementioned ibuprofen, aspirin and diuretics.

It is important to maintain a health blood platelet count and ensure proper platelet function and proper bone marrow function.

What Does Eastern Medicine Say?*

According to the National Center for Complementary and Alternative Medicine, TCM or Traditional Chinese Medicine is based on a different and unique world view:

“Underlying the practice of TCM is a unique view of the world and the human body that is different from Western medicine concepts. This view is based on the ancient Chinese perception of humans as microcosms of the larger, surrounding universe—interconnected with nature and subject to its forces. The human body is regarded as an organic entity in which the various organs, tissues, and other parts have distinct functions but are all interdependent. In this view, health and disease relate to balance of the functions.”

http://nccam.nih.gov/health/whatiscam/chinesemed.htm#concepts

So according to the Eastern Medicine philosophy, all ‘dis’-ease is caused by imbalance in the body. They believe that supporting the body is the key to health, wellness and longevity with a high quality of life. They believe that supporting healthy platelet function will create conditions where abnormal platelets can’t exist. Eastern Medicine has used the essential herbs Rehmannia Chinese Foxglove, Alisma Rhizoma Root, Astragalus Membranaceus, Thlaspi Arvense, Eclipta Prostrata Han Lian Cao, Phyllanthus Urinaria Euphorbiaceae, Dioscorea Batatas Chinese Yam, Ophiopogonis Japonicus Tuber Mai Men Dong, Dried Black Bamboo Juice Phyllostachys Nigra, Agrimonia Pilosa Hairy Agrimony, Sarcandra Glabra Cao Shan Hu and Artemisia Capillaris for platelet health support.*

Article Sources:
http://www.nhlbi.nih.gov/health/health-topics/topics/thcp
http://www.mayoclinic.com/health/thrombocytopenia/DS00691
http://en.wikipedia.org/wiki/Thrombocytopenia
http://www.emedicinehealth.com/thrombocytopenia_low_platelet_count/article_em.htm

Blood Platelets

May 8th, 2012

This article is meant to serve as a general primer on Blood Platelets.

What Are Blood Platelets?

Platelets are one of three major types of blood cells in the body (along with red blood cells and white blood cells). They are the smallest of the three types of blood cells, coming in at 1/5 the diameter of red blood cells, and numbering 150k-450k per microliter of blood in a healthy human, according to the NIH.

Red and White Blood Cell with Platelet

Scanning microscope shot of a red blood cell left, platelet center, white blood cell right. From http://en.wikipedia.org/wiki/Platelet

Platelets, like white blood cells and red blood cells, are produced by your bone marrow. They typically have a 7 to 10 day lifespan, so they keep your bone marrow busy, constantly producing more platelets. Blood platelets are clear cell fragments that do not have a nucleus with DNA. They are also known a thrombocytes.

What Do Blood Platelets Do?

The main job of platelets is to prevent bleeding. Platelets do this by clumping together and clotting. If you suffer a cut, it is the platelets in your blood that begin to stick together around the wound and prevent too much exposed blood from flowing out. Normal blood clotting around a wound is a good thing, but abnormal blood clots can cause stroke and heart attack.

What Do Blood Platelets Have To Do with My Health?

Platelets do more than just clump together and clot. They offer complex growth factors believed to play a role in the body’s regenerative processes. But that’s another article on platelet growth factors.

The main concern with platelets is whether they are working correctly (often referred to as normal platelet function or normal blood platelet function). If platelet function is impaired, excessive bleeding or excessive clotting can occur, and this can lead to platelet disorders. Low platelet counts can cause excessive bleeding or bruising, high platelet counts can cause abnormal clotting, and abnormalities with the platelets can cause problems, as well. Platelet abnormalities (thrombocytopathy) can occur with a low platelet count, a high platelet count, or with a normal platelet count. So just as Goldilocks wanted the third bowl of porridge that was neither too hot or too cold, you want the right number of platelets, functioning normally, that can ensure you don’t keep bleeding after an injury, but that you don’t also form unecessary blood clots.

In summary, there are three things that may be cause for worry with blood platelets:

  1. A low blood platelet count (thrombocytopenia)
  2. A high blood platelet count  (thrombocytosis)
  3. Abnormal platelet function (thrombocytopathy)

Low Blood Platelet Count (Thrombocytopenia)

Low blood platelets counts can cause excessive bleeding when there aren’t enough platelets in your blood to clot and eventually stop bleeding. Normally, you should have 150,000 to 450,000 platelets per microliter (one millionth of a liter) of blood in your body. If your blood platelet count falls below that, then you could have a low blood platelet count. The technical term for a problematic low platelet count (especially 50,000 platelets per microliter and lower) is thrombocytopenia. Click Here for Low Blood Platelets

High Blood Platelet Count (Thrombocytosis)

Blood Platelets

A blood platelet can be seen in the upper left, much smaller than the stained red blood cells. From http://en.wikipedia.org/wiki/Platelet

If the number blood platelets is too high, this can lead to thrombosis, the formation of bad blood clots (and blood clots can cause a whole host of problems, including stroke, myocardial infarction, pulmonary embolism or the blockage of blood vessels heading to other parts of the body).

Since the purpose of platelets is to clot, this can seem a little confusing. Basically, you want platelets to naturally string together when you have an injury, to minimize blood loss. But you don’t want your bone marrow to produce so many excess platelets that they stick together and cause a blood clot where you don’t need it. That can block blood flow and cause real problems, depending on where it is in the body. Click for high blood platelets article.

Abnormal Platelet Function (Thrombocytopathy)

This is when the platelets that DO exist are not doing their job as they should due to an abnormality of platelets, known as thrombasthenia. This is a very rare but very serious problem and can occur with low platelets, normal platelets or high platelets. Click for abnormal platelet function article.

How Can I Avoid Abnormal Blood Platelet Counts or Function?*

This is the 64 thousand dollar question and in modern medicine appears not to have much of an answer, and is really beyond the scope of this article.

Idiopathic thrombocytopenia purpura is an autoimmune platelet condition that has “no known cause” right in the name, the word idiopathic. If there is no known cause, prevention then becomes a challenge. Some say that I.T.P. is an outmoded name since so much is known about the “cause” of I.T.P, more specifically that it is an autoimmune disorder where the immune system attacks the thrombocytes or platelets. But that “cause” is really another layer of symptoms, and doesn’t answer the question why, why does the immune system attack the thrombocytes?*

The bottom line is that as of yet, most all of the information available about blood platelet disorders deals with treating the symptoms. The true causes other than genetics, or genetic mutation remain a mystery. Not so for health care practitioners dealing with Eastern Medicine modalities and traditional medicinal practices. They believe the answer is simple, lack of balance in the body. That’s a pretty vague and holistic statement, however there has been some success in this approach for many thousands of years.*

Does Alternative Medicine Have An Opinion?*

Need we ask? PDSA.org is a site dedicated to I.T.P or Idiopathic Thrombocytopenic Purpura which is the bleeding disorder that occurs mostly in children. The site covers a lot of ground including all kinds of treatment. They mention many alternative approaches to I.T.P. treatment including Chinese herbal remedies and Ayurvedic medicine http://www.pdsa.org/treatments/complementary/traditional-chinese-ayurvedic.html.

Blood Platelets Conclusion

Thrombocytes are critically important to health and more and more is being learned just how critical they are. We hope you have enjoyed this short primer on blood platelets.

Thanks,

Get Well Natural LLC

Sources:

http://www.fi.edu/learn/heart/blood/platelet.html

http://en.wikipedia.org/wiki/Platelet

http://www.nlm.nih.gov/medlineplus/plateletdisorders.html

http://ghr.nlm.nih.gov/glossary=platelets

http://ghr.nlm.nih.gov/condition/myh9-related-disorder

http://ghr.nlm.nih.gov/condition/essential-thrombocythemia

http://ghr.nlm.nih.gov/condition/thrombotic-thrombocytopenic-purpura

http://ghr.nlm.nih.gov/search?query=platelet+disorders&Search=

 

http://www.pdsa.org/treatments/complementary/traditional-chinese-ayurvedic.html

http://www.pdsa.org/itp-treatments/herbal-remedies.html

http://www.pdsa.org/itp-treatments/ayurvedic-medicine.html

http://www.itmonline.org/arts/itp.htm

Increase Platelet Count an Eastern Medicine View

December 21st, 2010

Are you looking to increase platelet counts? *

Many want to increase their platelet count. Eastern medicine dietary herb practitioners believe that dietary herbal supplements can support the body’s ability to produce platelets normally.* The object is to enable yourself, your very own body, to do what the body is already able to do, be alive, normal, healthy. They believe that all disease is truly “dis-ease”, which they believe to be an out of balance body.*

To increase platelet counts means that the body must be functioning normally, in order for the body to naturally normalize a low platelet count up to a normal platelet count. Supporting the body’s innate and natural ability to produce normal platelet count levels was the object of the Doctors and Herbalists who developed the legendary line of healthy platelet support products brought to you by Get Well Natural LLC, the original source. *

They believe, and have demonstrated, that health can be optimally supported with specific herbal formulas as part of a healthy diet and lifestyle.* Their herbal formulas such as those contained in Blood Well, Restore Immune II, (both are in the ITP Kit) & the single extracts Agrimonia & Artemisia Capillaris have a long history of use in their private practices with many satisfied patients.*

Are you looking to do more research on how to increase platelet count levels? Click below to find out what lifestyle approaches Dr. Graeme Shaw MD believes to best support optimal bone marrow function and healthy platelet count levels.

Click here for platelet health support information

Low Platelet Levels

November 26th, 2010

Low platelet levels a concern?*

How to avoid low platelet levels? The body’s power to deflect low platelet levels can be supported through dietary herbal supplements and lifestyle according to Eastern Medicine practitioners. According to them, what this means is that the body, when in balance and healthy, has everything it needs to keep platelets normal. So if the body is supported to stay in balance, then the body may be able to maintain healthy platelet levels is their theory, and their practice.*

ITP Has “No Known Cause” according to Western Medicine, but what about Eastern Medicine?*

Western Medicine trained doctors believe that idiopathic thrombocytopenic purpura the platelet and bruising condition known as “I.T.P.” has no known causes that can exhibit low platelet levels. The Doctors and Herbalists who developed the ITP Kit for Get Well Natural LLC believe, as Eastern medicine practitioners believe, that the cause is emotional or physical stress. They believe that the body can indeed heal and maintain itself without any Western Medicine drugs or surgery. Along this line, these formula developing doctors have discovered key herbal nutrients that work best at supporting the body’s natural platelet systems and platelet count levels.  Get Well Natural provides these legendary platelet supportive products in its ITP Kit (includes 2 bottles of Blood Well and 2 bottles of Restore Immune II.  This herbal kit can be taken twice daily as an important part of your overall platelet health holistic protocol.*

Click Here for the ITP Kit Now

Herbs to Increase Platelets

October 25th, 2010

Herbs to Increase Platelets through Platelet Health Support*

In Eastern medicine it is believed that the body performs all health functions without the need for external drugs, but proper balance and support is needed to accomplish this goal. It is the body that can “restore” itself they believe. It is when the body is out of balance that sickness and disease occurs they believe. So herbs that directly increase platelets don’t really exist, only dietary herbs that support the body’s innate ability. It might be splitting hairs but it’s an important distinction critical to the Eastern medicine philosophy. When the body is stress free and fed healthy foods and supplements that support it, Eastern Medicine practitioners understand that vibrant health and longevity ensue.*

Are You Researching How to Use Dietary Herbs to Increase Platelets Counts?*

Eastern Medicine Practitioners believe herbs are an important part of any protocol focused on increasing platelet counts.*

In Eastern medicine it is believed that the body performs all health. It is the body that can “restore” itself they believe. Like most Eastern medicine practitioners, the creators of Get Well Natural’s ITP Kit believe that all health stems from natural body energy and balance.* They believe that with specific herbs supplemented through diet, blood platelet body systems can be better supported, assisting the body to achieve balance. They believe that a properly balanced body can avoid low platelets, or high platelets, or any abnormal platelets and restore platelet levels.*

The legendary ITP Kit that contains Restore Immune II and Blood Well is believed by its creators to be the perfect herbal combination for healthy platelet counts.*

Click Here to Try the ITP Kit with herbs to increase platelets* 100% Satisfaction Guaranteed!

Low Blood Platelets and Ideopathic Thrombocytopenic Purpura (I.T.P.)

August 28th, 2010

Ideopathic Thrombocytopenic Purpura (I.T.P.) Usually Means Low Platelet Levels and Bruising*

What causes low blood platelets?

The condition known as I.T.P. (Idiopathic Thrombocytopenic Purpura) is idiopathic, meaning no known cause, thrombocytopenic meaning related to thrombocytopenia (low platelets or thrombocytes) with bruising, or purpura. I.T.P. is believed to be an autoimmune condition according the the NHLBI:

What Causes Idiopathic Thrombocytopenic Purpura?

In most cases, it’s believed that an autoimmune response causes idiopathic thrombocytopenic purpura (I.T.P.).

Normally, the immune system makes antibodies (proteins) to fight off germs or other harmful things that enter the body. In I.T.P., however, the immune system attacks and destroys the body’s platelets by mistake. Why this happens isn’t known.

Children who get acute (short-term) I.T.P. often have had recent viral infections. It’s possible that the infection somehow “triggers” or sets off the immune reaction that leads to I.T.P. in these children. I.T.P. in adults, on the other hand, doesn’t seem to be linked to infections.

According to the NIH low blood platelets is a type of platelet disorder:

Platelets help wounds heal and prevent bleeding by forming blood clots. Your bone marrow makes platelets. Problems can result from having too few or too many platelets, or from platelets that do not work properly.

If your blood has a low number of platelets, you can be at risk for mild to serious bleeding. If your blood has too many platelets, you may have a higher risk of blood clots. With other platelet disorders, the platelets do not work as they should. For example, in von Willebrand Disease, the platelets cannot stick together or cannot attach to blood vessel walls. This can cause excessive bleeding.

Treatment of platelet disorders depends on the cause.

NIH: National Heart, Lung, and Blood Institute

What do Eastern Medicine Practitioners Believe to be the Cause of Idiopathic Thrombocytopenic Purpura?

Most Eastern Medicine Doctors believe that the cause of most disease conditions is due to an imbalance and/or disharmony within the body, energetic and organ system. According to the developers of Get Well Natural’s ITP Kit products, the cause of Idiopathic Thrombocytopenic Purpura is an overload of physical or emotional stress on the body*

The ITP Kit (Restore Immune II, Blood Well)

Get Well Natural LLC is the exclusive supplier for the ITP Kit which contains Blood Well and Restore Immune II. Doctors and Herbalists developed this herbal supplement over years of successful practice in Vietnam and Russia using the Eastern Medicine holistic health philosophy.*

Read More About the ITP Kit

Agrimonia Pilosa

July 31st, 2010

Agrimonia Pilosa

Agrimonia Pilosa

Agrimonia Pilosa, a single herbal extract, has long been used in Traditional Chinese Medicine (TCM) practices due to its blood platelet coagulation supportive qualities. Agrimonia Pilosa is used to promote blood clotting and control bleeding. Bown. D. Encyclopaedia of Herbs and their Uses. Dorling Kindersley, London. 1995 ISBN 0-7513-020-31 (www.PFAF.org)

Get Well Natural and Agrimonia Pilosa

Agrimonia is contained in Restore Immune II, but it also is available as a separate single herb extract product. Many of Get Well Natural’s customers report very satisfying results when they add more Agrimonia to their dietary protocol.  Many Get Well Natural customers take Agrimonia (90 Capsules) in addition to the Agrimonia ingredient contained in Restore Immune II, one of the products in Get Well Natural LLC’s ITP Kit. According to the Doctors and Herbalists who developed the ITP Kit, their patients have seen great success in supporting healthy platelet levels. This remarkable herb merits further study to be sure, meanwhile Agrimonia is being used by many satisfied customers according to them.*

Click Here for More Information about Healthy Platelet Level Support

Introducing the ITP Kit

April 13th, 2010

The ITP Kit from Get Well Natural LLC

How to Increase Platelets? Support Your Own Body’s Ability to Increase Platelets*

This is the Eastern medicine philosophy. The body is believed to have the innate ability to remain in a state of health and balance if given the proper support. This goes along with “diet and exercise” quite nicely. So diet really is important for health, and gives the body the best chance to not only maintain good health, but to cure itself naturally. When food and exercise alone are not enough, the ITP Kit developers believe that herbal dietary supplementation can be a crucial part of any healthy protocol*

Support Platelet Health*

Master Herbalists and Medical Doctors discovered techniques that naturally support the body’s ability to increase platelets.*  These developing doctors realized that integrating a person’s organ balance or imbalance, lifestyle, environment, diet, and herbal supplementation was the best way to support the body’s own abilities to produce healthy blood platelets.*

For many years Get Well Natural LLC products have been approaching platelet health support with these Doctor’s recommended formulas such as the ITP Kit containing both Blood Well and Restore Immune II.*

Click Here to Try Your ITP Kit Platelet Health Support Herbs…

*These statements have not been evaluated by the U.S. Food and Drug administration. These products are not intended to diagnose, treat, cure, or prevent any disease.